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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPAPDC1A
All Species:
11.82
Human Site:
S257
Identified Species:
18.57
UniProt:
Q5VZY2
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q5VZY2
NP_001025230.1
271
30395
S257
E
E
R
P
T
A
D
S
A
P
S
L
P
L
E
Chimpanzee
Pan troglodytes
XP_001170623
223
25141
S210
F
Q
D
K
L
V
L
S
T
A
Q
K
P
G
D
Rhesus Macaque
Macaca mulatta
XP_001092746
343
37863
A316
Y
Y
P
P
L
T
D
A
E
C
H
K
P
F
Q
Dog
Lupus familis
XP_535038
333
36609
S319
D
E
R
P
T
A
D
S
A
P
S
M
P
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q0VBU9
271
30425
S257
E
E
R
P
T
A
D
S
A
P
S
L
P
L
E
Rat
Rattus norvegicus
O08564
282
31978
S255
D
F
F
K
T
T
E
S
N
K
E
R
K
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514919
461
51675
G263
R
F
Y
A
H
Q
D
G
D
E
E
A
T
F
P
Chicken
Gallus gallus
XP_426544
322
36285
N308
E
E
R
P
T
A
D
N
A
T
G
L
P
L
E
Frog
Xenopus laevis
Q6GQ62
226
25153
Q213
K
G
R
M
S
G
A
Q
E
R
K
L
S
T
P
Zebra Danio
Brachydanio rerio
XP_002664129
282
31516
L264
P
A
S
Q
D
Q
P
L
P
T
D
N
A
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623887
268
30640
V254
L
N
Q
I
H
C
C
V
G
E
M
L
S
Q
L
Nematode Worm
Caenorhab. elegans
Q10022
341
39009
R308
S
E
D
E
E
R
H
R
L
D
A
V
L
P
S
Sea Urchin
Strong. purpuratus
XP_787511
258
29394
N244
L
Q
E
Y
N
T
N
N
A
I
S
T
R
I
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9XI60
290
32684
M276
D
V
Q
D
S
A
G
M
N
H
L
S
V
R
Q
Baker's Yeast
Sacchar. cerevisiae
Q05521
289
33495
H273
T
L
E
E
A
V
T
H
Q
R
I
P
D
E
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
51.2
48
77.7
N.A.
99.2
25.5
N.A.
48.1
77.3
52.4
71.2
N.A.
N.A.
47.9
24.3
46.1
Protein Similarity:
100
64.9
60
79.8
N.A.
99.2
41.1
N.A.
53.3
80.4
63.4
83.6
N.A.
N.A.
66.7
39.8
64.2
P-Site Identity:
100
13.3
20
86.6
N.A.
100
13.3
N.A.
6.6
80
13.3
0
N.A.
N.A.
6.6
6.6
13.3
P-Site Similarity:
100
26.6
33.3
100
N.A.
100
33.3
N.A.
6.6
86.6
26.6
0
N.A.
N.A.
13.3
20
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.5
31.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.4
50.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
7
7
34
7
7
34
7
7
7
7
0
0
% A
% Cys:
0
0
0
0
0
7
7
0
0
7
0
0
0
0
0
% C
% Asp:
20
0
14
7
7
0
40
0
7
7
7
0
7
0
14
% D
% Glu:
20
34
14
14
7
0
7
0
14
14
14
0
0
14
34
% E
% Phe:
7
14
7
0
0
0
0
0
0
0
0
0
0
14
0
% F
% Gly:
0
7
0
0
0
7
7
7
7
0
7
0
0
7
0
% G
% His:
0
0
0
0
14
0
7
7
0
7
7
0
0
0
0
% H
% Ile:
0
0
0
7
0
0
0
0
0
7
7
0
0
7
0
% I
% Lys:
7
0
0
14
0
0
0
0
0
7
7
14
7
0
0
% K
% Leu:
14
7
0
0
14
0
7
7
7
0
7
34
7
27
7
% L
% Met:
0
0
0
7
0
0
0
7
0
0
7
7
0
0
0
% M
% Asn:
0
7
0
0
7
0
7
14
14
0
0
7
0
0
0
% N
% Pro:
7
0
7
34
0
0
7
0
7
20
0
7
40
7
20
% P
% Gln:
0
14
14
7
0
14
0
7
7
0
7
0
0
7
14
% Q
% Arg:
7
0
34
0
0
7
0
7
0
14
0
7
7
7
0
% R
% Ser:
7
0
7
0
14
0
0
34
0
0
27
7
14
0
14
% S
% Thr:
7
0
0
0
34
20
7
0
7
14
0
7
7
14
0
% T
% Val:
0
7
0
0
0
14
0
7
0
0
0
7
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
7
7
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _